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St. Louis Rams San Francisco 49ers Betting Pick

March 11th, 2026
 

Rams 49ers Pick

Take the Rams +6  at Brobury Sports

Wager Now!
Both of these long time NFC West rivals are coming off of byes in week 9, and both are in desperate need of a victory this weekend, especially the 49ers.  The Rams, although in first in the dreadful NFC West, have yet to win a single game on the road this season.  Despite winning 2 out of their past 3, the 49ers have just a 2-6 record, with both wins coming at home.

The most surprising stat among these two teams is St. Louis’ defence.  They are ranked 10th in the league in total defense.  This has lots to do with the amount of pressure they are putting on opposing quarterbacks, as they have 23 sacks as a team through 8 games this season.  To put this number in comparison to all of last years Rams sack totals, the team had just 25 sacks last season.

Both of these defences are solid as a whole, but one big difference amongst the two would be their pass defence.  The 49ers rank 23rd in average yards per pass attempt with 7.4 yards.  The Rams are an impressive 5th with 6.4 yards per attempt.  The Rams are also 10th in the league in opposing teams quarterback rating by allowing an average qb rating of 76.3.  The 49ers are 24th in the same category with an average rating of 90.2 allowed.
NFL Betting

Expert Pick: St. Louis Rams +6

I think this matchup is going to be a low scoring tightly contested match with either team winning by a field goal.  I don’t know if the Rams can pull out a win on the road against a tough divisional opponent with a team thats better than their record indicates, as they’ve lost 4 games by field goals, but I do believe they cover the spread.  The Rams on the money line may also be a solid bet this weekend, as the Rams are getting +225.

Final Score: 49ers 17 Rams 14

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